Meeting Banner
Abstract #1066

Water suppression in the human brain with hypergeometric RF pulses for single- and multi- voxel MR spectroscopy

Kimberly Chan1,2,3, Ronald Ouwerkerk4, and Peter Barker2,3

1Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, United States, 2Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, Baltimore, MD, United States, 3F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, 4Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, United States

In this study, a novel water suppression sequence with hypergeometric RF pulses (HGWS) is investigated and compared to the commonly used VAPOR sequence in simulations, single and multi- voxel acquisitions. In simulations, HGWS and VAPOR are insensitive to B1 and water T1 variations, but with no B1 variation, HGWS has a lower average residual water fraction than that of VAPOR. In vivo, HGWS provides better water suppression than VAPOR in both single-voxel and multi-voxel acquisitions with a shorter sequence duration.

This abstract and the presentation materials are available to members only; a login is required.

Join Here