The adult aging process affects human brains in different ways and becomes more prone to neurodegenerative diseases. MRE has shown it’s sensitivity to both changes within healthy brains and identifying biomarkers in diseased brains. This study builds on previous MRE aging research and adds higher-resolution, full-coverage MRE imaging and the ability to identify tissue anisotropy, or lack thereof, with the multi-excitation experiment. We were able to identify important anisotropic differences in the loss modulus for some white matter (WM) regions within the young group and a loss of group-level anisotropy in the select WM regions in the older group.
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