MR Elastography of the hippocampus has been associated with memory performance in young adults and thus may have potential as a novel imaging biomarker for Alzheimer’s disease (AD). In healthy older-adults, hippocampal damping ratio ξ was significantly associated with performance on a verbal memory task. Due to greater hippocampal atrophy present in older populations, the contributions of voxels containing CSF were analysed. Stronger correlations with memory were found once CSF voxels were excluded, and when the left hippocampus was analysed separately. MRE of the hippocampus may be a sensitive marker for detecting early pathological changes in patients with AD.