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Abstract #1076

Usage of Octahedral Shear Strain Weights in the Inversion of Multifrequency MR Elastography

Cemre Ariyurek1,2, Bilal Tasdelen1,2, Eric Barnhill3, Arif Sanli Ergun4, Yusuf Ziya Ider1, and Ergin Atalar1,2

1Department of Electrical and Electronics Engineering, Bilkent University, Ankara, Turkey, 2National Magnetic Resonance Research Center (UMRAM), Ankara, Turkey, 3Radiological Sciences, Charité - Universitätsmedizin Berlin, Berlin, Germany, 4Department of Electrical and Electronics Engineering, TOBB-University of Economics and Technology, Ankara, Turkey

Multifrequency MR elastography (MMRE) is useful for compensating the influence of amplitude nulls on the elastogram by combining computations at different frequencies by amplitude-weighted averaging or directly without using weights. Previously, it was shown that strain‑SNR measures the quality of the data for reconstructing accurate elastography maps. Therefore, using octahedral shear strain (OSS) weights may lead to more accurate elastograms. In this study, k-MDEV and multifrequency Helmholtz inversion have been used. Including OSS-weights in the inversions yielded more reliable elastograms for simulation and experiment phantom. Furthermore, elastograms in higher resolution were obtained for the brain model and human brain data.

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