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Abstract #1077

Motion-resolved UTE based Pulmonary Quantitative Susceptibility Mapping

Xucheng Zhu1,2, Hongjiang Wei3, Kevin M. Johnson4,5, Scott K. Nagle4,5, Wenwen Jiang6, Joseph Cheng7, Shreyas S. Vasanawala7, Michael Lustig3, Chunlei Liu3, and Peder E.Z. Larson1,2

1Bioengineering, UCSF&UC Berkeley, San Francisco, CA, United States, 2Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States, 3Department of Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA, United States, 4Department of Medical Physics, University of Wisconsin, Madison, Madison, WI, United States, 5Department of Radiology, University of Wisconsin, Madison, Madison, WI, United States, 6Heartvista Inc., Los Altos, CA, United States, 7Department of Radiology, Stanford University, Stanford, CA, United States

Pulmonary MRI is challenging due to many factors, such as short T2* relaxation time and respiratory motion corruption. However, the large susceptibility differences in the lungs from blood oxygenation and O2 content might provide more information related to pulmonary function. In this work, we combined ultra-short TE(UTE) acquisition, quantitative susceptibility mapping(QSM), and motion-resolved reconstruction techniques together to look at the susceptibility contrast in the lung and changes in different motion states. According to the results, this technique provides extra contrast information compared to traditional intensity images, and shows susceptibility changing of lung in different respiration states.

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