Abstract #1077

Motion-resolved UTE based Pulmonary Quantitative Susceptibility Mapping

Xucheng Zhu^1,2, Hongjiang Wei³, Kevin M. Johnson^4,5, Scott K. Nagle^4,5, Wenwen Jiang⁶, Joseph Cheng⁷, Shreyas S. Vasanawala⁷, Michael Lustig³, Chunlei Liu³, and Peder E.Z. Larson^1,2

¹Bioengineering, UCSF&UC Berkeley, San Francisco, CA, United States, ²Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States, ³Department of Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA, United States, ⁴Department of Medical Physics, University of Wisconsin, Madison, Madison, WI, United States, ⁵Department of Radiology, University of Wisconsin, Madison, Madison, WI, United States, ⁶Heartvista Inc., Los Altos, CA, United States, ⁷Department of Radiology, Stanford University, Stanford, CA, United States

Pulmonary MRI is challenging due to many factors, such as short T2* relaxation time and respiratory motion corruption. However, the large susceptibility differences in the lungs from blood oxygenation and O₂ content might provide more information related to pulmonary function. In this work, we combined ultra-short TE(UTE) acquisition, quantitative susceptibility mapping(QSM), and motion-resolved reconstruction techniques together to look at the susceptibility contrast in the lung and changes in different motion states. According to the results, this technique provides extra contrast information compared to traditional intensity images, and shows susceptibility changing of lung in different respiration states.

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