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Abstract #1103

Validity extension of stimulated echoes to imaginary signals arising for double diffusion encoding of closed pores

Kerstin Demberg1, Frederik Bernd Laun2, Peter Bachert1, and Tristan Anselm Kuder1

1Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 2Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

We extend diffusion-weighted acquisitions using the stimulated echo acquisition mode (STEAM) to imaginary signals. In classical diffusion encoding, only real signals arise; however, for special applications of double diffusion encoding (DDE), complex signals arise, as shown here for diffusion pore imaging, a method that allows determining the shape of arbitrary closed pores filled with an NMR-detectable medium. It is shown that the phase information of complex signals is preserved under application of stimulated echoes: We show the analytically derived signal for DDE with STEAM and use Monte Carlo simulations for validation. Consequently STEAM can be employed for diffusion pore imaging.

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