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Abstract #1140

Optic Nerve Sheath Volume Changes Acutely in Response to Intracranial Pressure Change after Lumbar Puncture and CSF Drainage

John Oshinski1, Muhammad Islam1, Chansu Kim1, and Amit Saindane1

1Radiology and Imaging Sciences, Emory University, Atlanta, GA, United States

This study used 3D, T2W imaging of the brain to evaluate the optic nerve sheath (ONS) in 10 patients with idiopathic intracranial hypertension (IIH). Patients were imaged pre- and immediately post-lumbar puncture/CSF drainage. Images were reformatted to be perpendicular to the optic nerve and the volume of the ONS pre- and post-lumbar puncture was calculated. The study found that ONS volume decreased significantly within an 82 minute window in response to a reduction in CSF pressure, and this change can be quantitatively evaluated using MRI.

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