This study used 3D, T2W imaging of the brain to evaluate the optic nerve sheath (ONS) in 10 patients with idiopathic intracranial hypertension (IIH). Patients were imaged pre- and immediately post-lumbar puncture/CSF drainage. Images were reformatted to be perpendicular to the optic nerve and the volume of the ONS pre- and post-lumbar puncture was calculated. The study found that ONS volume decreased significantly within an 82 minute window in response to a reduction in CSF pressure, and this change can be quantitatively evaluated using MRI.
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