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Abstract #1225

New 4D-MRA approach named 4D-APACK by integrating 4D-PACK and AccASL for visualization of long transit time artery: Investigating hemodynamics accuracy and AVM clinical case

Yuta Akamine1, Makoto Obara1, Osamu Togao2, Shuhei Shibukawa3, Masami Yoneyama1, Tomoyuki Okuaki1, and Marc Van Cauteren4

1Philips Japan, Shinagawa, Tokyo, Japan, 2Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, 3Department of Radiology, Tokai University Hospital, Kanagawa, Japan, 4Philips Healthcare, Shinagawa, Tokyo, Japan

A new 4D-MRA approach named 4D-AccASL-PACK (4D-APACK) was implemented and images were acquired in six healthy volunteers and one AVM patient. 4D-APACK consists of 4D-PACK and acceleration-selective arterial spin labeling (AccASL) for obtaining efficiently both dynamic information and ATT independent visualization of very slow flow. 4D-APACK replaces last timepoint data of 4D-PACK with AccASL. To investigate hemodynamics accuracy for 4D-APACK, ATT correlation between 4D-pCASL and 4D-APACK and contamination of sinuses were measured. The vessel visualization of MCA M1 to M4 were compared with 4D-pCASL. We demonstrate that 4D-APACK brings reliable hemodynamic information comparable to 4D-pCASL, while retaining MCA visualization performance.

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