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Abstract #1266

The presence of brown adipose tissue is associated with thyroid function in subjects with low and normal BMI

Daniela Franz1, Dominik Weidlich1, Jan Syväri1, Maximilian N. Diefenbach1, Christina Holzapfel2, Theresa Drabsch2, Thomas Baum3, Holger Eggers4, Ernst J. Rummeny1, Hans Hauner2, and Dimitrios C. Karampinos1

1Department of Diagnostic and Interventional Radiology, Technical University of Munich, Munich, Germany, 2Else Kröner Fresenius Center for Nutritional Medicine, Technical University of Munich, Munich, Germany, 3Department of Diagnostic and Interventional Neuroradiology, Technical University of Munich, Munich, Germany, 4Philips Research Laboratory, Hamburg, Germany

Brown adipose tissue (BAT) is important for energy and glucose metabolism in humans. Thyroid hormones regulate BAT development and function. Proton density fat fraction (PDFF) mapping based on a multi-echo gradient echo acquisition enables spatially-resolved fat quantification and can be indicative of the presence of BAT in adults. This study investigates the relationship between supraclavicular PDFF as surrogate marker for BAT, and serum levels of free thyroxine and free triiodothyronine with body mass index (BMI) as grouping variable.

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