Abstract #1275

Optimisations for ultra-high resolution MRSI of the brain at 7 T: Towards even higher resolutions and faster measurements

Gilbert Hangel^1,2, Bernhard Strasser³, Michal Povazan^4,5, Eva Hečková^1,2, Stephan Gruber^1,2, Philipp Moser^1,2, Lukas Hingerl^1,2, Siegfried Trattnig^1,2, and Wolfgang Bogner^1,2

¹High Feld MR Centre, Medical University of Vienna, Vienna, Austria, ²Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, ³Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States, ⁴Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, United States, ⁵F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States

Recently, ultra-high resolution (UHR-) MRSI of the brain at 7 T was successfully demonstrated, allowing metabolic mapping at near-anatomical resolution. With this work, we propose further optimised sequences, one for shorter measurement times of under 5 min and one for even higher in-plane resolutions down to 12 µL, which will allow a more flexible application of UHR_MRSI, and show their possibilities and limitations. Furthermore, the effects of slice thickness for UHR-MRSI were investigated with a second set of measurements.

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