HERMES with single-voxel PRESS localization has been used to simultaneously edit multiple compounds. It’s often desirable to measure spectra from multiple brain regions, using MR spectroscopic imaging (MRSI). This study examined the feasibility of HERMES editing of GABA and GSH with a PRESS-localized MRSI sequence at 3T, and compared it to conventional MEGA-edited MRSI acquisitions. It’s found that adding symmetrical lipid suppression pulses to HERMES allows the sequence to be used in vivo and has an editing efficiency equivalent to that of separate acquisitions of GABA and GSH using MEGA-PRESS MRSI without an increase in measurement variability relative to MEGA-PRESS.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords