Modern magnetic resonance spectroscopic (MRS) pulse sequences frequently overlook the issue of unwanted coherence pathways. A novel and robust algorithm which only requires input of the desired coherence(s) was developed to optimally crush all unwanted coherence pathways for any MRS pulse sequence. Experiments were performed on the GE BRAINO phantom comparing crusher schemes obtained from the literature with those obtained from the developed optimization algorithm for sLASER and MEGA-sLASER. The results demonstrate that the effects of unwanted coherences can be drastically reduced through the implementation of an optimized crusher scheme, without the need for additional or stronger crushers.
This abstract and the presentation materials are available to members only; a login is required.