Abstract #1330

Estimation of T2 Relaxation Times of Downfield Peaks in Human Brain at 9.4 T

Saipavitra V. Murali Manohar¹, Tamas Borbath¹, Nicole Fichtner^2,3, Ioannis Angelos Giapitzakis¹, Daniel Zaldivar¹, Roland Kreis³, and Anke Henning^1,4

¹Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, ²Institute for Biomedical Engineering, UZH and ETH Zurich, Zurich, Switzerland, ³Depts. Radiology and Biomedical Research, University of Bern, Bern, Switzerland, ⁴Institute of Physics, Ernst-Moritz Arndt University Greifswald, Greifswald, Germany

T₂ relaxations times for the downfield metabolites in human brain ¹H MR spectra were estimated at 9.4 T. A possible new peak at 8.35 ppm with rapid T₂ decay is reported. Due to the use of a non-water suppressed MRS method, the T₂ of slowly exchanging peaks could be assessed. The shorter T₂relaxation times in the downfield compared to the upfield spectral areas leads us to suspect a macromolecular contribution, while also exchange effects may contribute to the short apparent T₂s.

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