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Abstract #1330

Estimation of T2 Relaxation Times of Downfield Peaks in Human Brain at 9.4 T

Saipavitra V. Murali Manohar1, Tamas Borbath1, Nicole Fichtner2,3, Ioannis Angelos Giapitzakis1, Daniel Zaldivar1, Roland Kreis3, and Anke Henning1,4

1Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, 2Institute for Biomedical Engineering, UZH and ETH Zurich, Zurich, Switzerland, 3Depts. Radiology and Biomedical Research, University of Bern, Bern, Switzerland, 4Institute of Physics, Ernst-Moritz Arndt University Greifswald, Greifswald, Germany

T2 relaxations times for the downfield metabolites in human brain 1H MR spectra were estimated at 9.4 T. A possible new peak at 8.35 ppm with rapid T2 decay is reported. Due to the use of a non-water suppressed MRS method, the T2 of slowly exchanging peaks could be assessed. The shorter T2 relaxation times in the downfield compared to the upfield spectral areas leads us to suspect a macromolecular contribution, while also exchange effects may contribute to the short apparent T2s.

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