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Abstract #1331

Multivariate Analysis of Developmental-Dependent Differences in Metabolites in White and Gray Matter: An Ultra-Short TE 1H MRS Study at 3T

Jack Knight-Scott1

1Radiology, Children's Healthcare of Atlanta, Atlanta, GA, United States

Application of multivariate analysis of variance (MANOVA) to a developmental data set of 1H spectra from white and gray matter brain tissue shows not only significant tissue differences but also significant gender and age differences. By specifically controlling for metabolite correlations, MANOVA results show higher sensitivity and power than individual ANOVAs.

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