On spectrally selective measurements of irreversible and reversible transverse relaxation rates from single voxel, single echo time PRESS acquisitions

We developed a methodology to measure the reversible and irreversible transverse relaxation rates R₂' and R₂, respectively, of multiple spectral peaks from spectroscopic sampling of both sides of a single spin echo. The methodology was applied to resonances in muscle and brain and the irreversible relaxation rates R₂ were compared with conventional measurements made from right side only spectra acquired at multiple PRESS echo times.