Abstract #1366

Metabolic imaging of glioblastoma using hyperpolarized 13C-MRI - glycolytic metabolism in cancer stem cell-like cells.

Tatsuya Kawai¹, Jeffery Brender², Kevin Camphausen¹, and Murali C Krishna²

¹Radiation Oncology Branch, National Cancer Institute, NIH, Bethesda, MD, United States, ²Radiation Biology Branch, National Cancer Institute, NIH, Bethesda, MD, United States

Dynamic nuclear polarization-MRI along with hyperpolarized [1-13C] pyruvate was conducted to evaluate the difference in glycolytic profile between a glioblastoma cell line and cancer stem-like cells using the orthotopic xenograft mouse model.

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