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Abstract #1386

Effect of Fat-contamination and Fat-suppression on T2 Quantitation of Knee Articular Cartilage In Vivo

Petri Paakkari1, Stefan Zbyn1,2, Mikko J Nissi3, Eveliina Lammentausta4, Miika T Nieminen1,2,4, and Victor Casula1,2

1Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, 2Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland, 3Department of Applied Physics, University of Eastern Finland, Kuopio, Finland, 4Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland

This study aims to investigate the effect of fat contamination and fat suppression (FS) on in vivo T2 mapping of knee cartilage. Four volunteers were imaged on a 3T MRI scanner and T2 values were calculated in several regions of tibiofemoral cartilage using a MSME sequence with and without FS. The use of FS improved repeatability of cartilage segmentation in several regions and reduced the chemical shift artifacts. However, the regional heterogeneity in FS sequence introduced further uncertainties in T2 measurements.

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