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Abstract #1433

Feasibility of monosodium urate assessment using multi-echo gradient echo based quantitative imaging

Seung hee Han1, Yoonho Nam1, Joon-Yong Jung1, and Won-Hee Jees1

1Seoul St.Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea

Gout is a common disease caused by monosodium urate (MSU) accumulation in joints. Although conventional MR imaging well describes generic features of inflammation, sensitivity of MSU is relatively low compared to dual energy CT. Because MSU has diamagnetic susceptibility, high sensitivity can be expected in magnetic susceptibility related contrast imaging. However, calcium is another diamagnetic material existing in joints. Therefore, distinguishing MSU and calcium is an essential step for imaging MSU. In this context, we investigate the feasibility of multi-echo gradient echo based quantitative imaging for MSU assessment.

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