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Abstract #1486

Temperature Induced Susceptibility Correlation in Adipose Tissues for MR-Guided Microwave Ablation

Yongyu Lin1, Kexin Deng1, Jinchao Wu2, Bingyao Chen3, Jiafei Yang3, Xing Wei3, and Kui Ying2,4

1Department of Biomedical Engineering, Tsinghua University, Beijing, China, 2Department of Engineering Physics, Tsinghua University, Beijing, China, 3Department of Orthopedics, First Affiliated Hospital of PLA General Hospital, Beijing, China, 4Key Laboratory of Particle and Radiation Imaging, Ministry of Education, Medical Physics and Engineering Institute, Tsinghua University, Beijing, China

Microwave ablation requires high temperature measurement accuracy to monitor the curative effect of the lesions. PRFS-based MR thermometry is the most commonly used temperature monitoring technique. However, PRFS is hampered by temperature-dependent magnetic susceptibility changes. It has been proved in the Quantitative Susceptibility Mapping(QSM) that susceptibility can be measured from the phase changes ,which is derived from Maxwell’s Equation. In this work, we proposed a practical method to calculate the errors caused by temperature-induced susceptibility changes based on the method in QSM. Both Simulation studies and microwave heating experiments validated the accuracy of the method.

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