Abstract #1486

Temperature Induced Susceptibility Correlation in Adipose Tissues for MR-Guided Microwave Ablation

Yongyu Lin¹, Kexin Deng¹, Jinchao Wu², Bingyao Chen³, Jiafei Yang³, Xing Wei³, and Kui Ying^2,4

¹Department of Biomedical Engineering, Tsinghua University, Beijing, China, ²Department of Engineering Physics, Tsinghua University, Beijing, China, ³Department of Orthopedics, First Affiliated Hospital of PLA General Hospital, Beijing, China, ⁴Key Laboratory of Particle and Radiation Imaging, Ministry of Education, Medical Physics and Engineering Institute, Tsinghua University, Beijing, China

Microwave ablation requires high temperature measurement accuracy to monitor the curative effect of the lesions. PRFS-based MR thermometry is the most commonly used temperature monitoring technique. However, PRFS is hampered by temperature-dependent magnetic susceptibility changes. It has been proved in the Quantitative Susceptibility Mapping(QSM) that susceptibility can be measured from the phase changes ,which is derived from Maxwell’s Equation. In this work, we proposed a practical method to calculate the errors caused by temperature-induced susceptibility changes based on the method in QSM. Both Simulation studies and microwave heating experiments validated the accuracy of the method.

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