Abstract #1485

Monitoring and Guidance on High-Intensity Focused Ultrasound Treatment by Multiple Fast Field Echo at 3.0 T MRI: Ex-Vivo Studies with Multiparametric Mapping

Jong-Min Kim^1,2, Chulhyun Lee³, Young-Seung Jo¹, Han-Jae Chung^1,2, Seong-Dae Hong^1,2, You-Jin Jeong^1,2, Jeong-Hee Kim⁴, and Chang-Hyun Oh^1,2

¹Department of Electronics and Information Engineering, Korea University, Seoul, Republic of Korea, ²ICT convergence technology for Health&Safety, Korea University, Sejong, Republic of Korea, ³Bioimaging Research Team, Korea Basic Science Institute, Chungbuk, Republic of Korea, ⁴Research Industrial for Advanced Industrial Technology, Korea University, Sejong, Republic of Korea

Because the multiple Fast Field Echo (mFFE) is rich in contrast manipulation, such as, in water-fat, susceptibility, conductivity, and temperature imaging, it is well suited to guide the thermal treatment. In this study, we sought to investigate the feasibility of the mFFE for monitoring and guidance of HIFU treatment in ex-vivo swine tissue. To demonstrate this study, we present the conductivity, temperature, and susceptibility mapping results. We have shown that the mFFE is very useful for guidance and monitoring of the HIFU treatment. Simultaneous temperature, conductivity, and susceptibility mapping has been tried using the mFFE sequence and its utility has been shown in this paper.

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