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Abstract #1494

Hybrid Proton Resonance Frequency Shift and Variable Flip Angle T1 Temperature Mapping using a Golden-Angle 3D Stack-of-Radial Technique

Le Zhang1, Tess Armstrong1,2, Samantha Mikaiel1,2, Alan Priester3, Rory Geoghegan4, Shyam Natarajan3,4, and Holden Wu1,2,4

1Radiological Sciences, University of California Los Angeles, Los Angeles, CA, United States, 2Physics and Biology in Medicine, University of California Los Angeles, Los Angeles, CA, United States, 3Urology, University of California Los Angeles, Los Angeles, CA, United States, 4Bioengineering, University of California Los Angeles, Los Angeles, CA, United States

Proton resonance frequency shift (PRF) is widely used for MR temperature mapping, but is not applicable in adipose tissues. T1 measurement is an alternative MR temperature mapping method that can be applied in adipose tissues. Combined PRF-T1 mapping has been evaluated for Cartesian MRI, but there is a lack of research for non-Cartesian techniques. In this work, we propose a new multi-echo 3D stack-of-radial technique that combines PRF and variable-flip-angle T1 measurement for MR temperature mapping. Preliminary results from laser ablation in phantoms demonstrate good agreement between temperature derived from both PRF and T1 compared to readings of temperature probes.

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