Abstract #1500

Mechanism of Stable Cavitation Induced Signal Intensity Changes in Fast Spin Echo Images

Cheng-Tao Ho¹, Chen-Hua Wu¹, Po-Hung Hsu², Hao-Li Liu³, Chih-Kuang Yeh¹, Ching-Hsiang Fan¹, Wen-Shiang Chen^4,5, and Hsu-Hsia Peng¹

¹Department Of Biomedical Engineering And Environmental Sciences, National Tsing Hua University, Hsinchu City, Taiwan, ²Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital, Taoyuan city, Taiwan, ³Department Of Electrical Engineering, Chang-gung University, Taoyuan city, Taiwan, ⁴Department Of Physical Medicine And Rehabilitation, National Taiwan University Hospital, Taipei city, Taiwan, ⁵Division Of Medical Engineering Research, National Health Research Institutes, Miaoli city, Taiwan

The purpose of this study was to comprehend the mechanism of stable cavitation (SC)-induced signal intensity (SI) changes by fast spin-echo images in a phantom with flowing MBs. We postulated that the different patterns of SI changes might be related to transmitting FUS pulses at different timing of k-line acquisitions. The SC-induced microstreaming and shear force could generate hypo- and hyper-SI changes, respectively. In conclusion, the illustration of the mechanism could be helpful for designing experiments in monitoring SC-induced SI changes.

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