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Abstract #1512

MRI-compatible intravital imaging window for longitudinal imaging of orthotopic mouse ovarian and pancreatic tumor stroma

Filip Bochner1, Vishnu Mohan1, Inbal Biton2, and Michal Neeman1

1Biological Regulation, Weizmann Institute of Science, Rehovot, Israel, 2Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel

Longitudinal multi-modal imaging of abdominal organs remains a challenge. In cancer research, where data acquired at multiple spatial and temporal scales is especially valuable, combination of powerful microscopic methods with MRI can yield complementary information about ECM and vascular components of the tumor stroma, both constituting a hallmark of pancreatic and ovarian tumors. Here we present the MRI compatible optical imaging window for longitudinal imaging of ovary and pancreas.

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