Abstract #1521

Repeatability of intravoxel incoherent motion diffusion-weighted MRI during chemoradiation therapy in head and neck cancers

Ramesh Paudyal¹, Nadeem Riaz², Vaios Hatzoglou³, Xie Peng^2,4, Jonathan Leeman², David Aramburu Nunez¹, Yonggang Lu⁵, Joseph O. Deasy¹, Nancy Lee², and Amita Shukla-Dave^1,3

¹Medical Physcis, Memorial Sloan Kettering Cancer Center, New York, NY, United States, ²Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, ³Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, ⁴Radiation Oncology, Shandong Cancer Hospital & Institute, Jinan, China, ⁵Radiology, Medical College of Wisconsin, Milwaukee, WI, United States

The aim of this study is to determine the repeatability of pre- treatment (TX) and intra- TX week 1 imaging metrics derived from intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI) in head and neck (HN) cancer patients during chemoradiation therapy. ADC, D, and D* imaging metrics showed better repeatability measurement than f in the metastatic node of HN cancer patients.

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