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Abstract #1521

Repeatability of intravoxel incoherent motion diffusion-weighted MRI during chemoradiation therapy in head and neck cancers

Ramesh Paudyal1, Nadeem Riaz2, Vaios Hatzoglou3, Xie Peng2,4, Jonathan Leeman2, David Aramburu Nunez1, Yonggang Lu5, Joseph O. Deasy1, Nancy Lee2, and Amita Shukla-Dave1,3

1Medical Physcis, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 2Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 3Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 4Radiation Oncology, Shandong Cancer Hospital & Institute, Jinan, China, 5Radiology, Medical College of Wisconsin, Milwaukee, WI, United States

The aim of this study is to determine the repeatability of pre- treatment (TX) and intra- TX week 1 imaging metrics derived from intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI) in head and neck (HN) cancer patients during chemoradiation therapy. ADC, D, and D* imaging metrics showed better repeatability measurement than f in the metastatic node of HN cancer patients.

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