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Abstract #1525

A comparison of pseudo continuous arterial spin labeling perfusion MRI (pCASL) and permeability imaging with dynamic contrast-enhanced MRI (DCE-MRI) in human rectal cancer

Yuichi Kumagae1, Yoshihiko Fukukurra1, Koji Takumi1, Hiroto Hakamada1, Tomoyuki Okuaki2, and Takashi Yoshiura1

1Department of Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan, 2Philips Electronics, Tokyo, Japan

Our purpose was to investigate potential correlations between the blood flow (BF) measured by pCASL and dynamic contrast-enhanced (DCE) MRI-derived pharmacokinetic parameters in rectal cancer. There were significant positive correlations between BF and Ktrans (p = 0.006, r = 0.579) or Kep (p = 0.002, r = 0.644). These results suggested that pCASL may have the potential to be a noninvasive alternative to DCE MRI.

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