Abstract #1525

A comparison of pseudo continuous arterial spin labeling perfusion MRI (pCASL) and permeability imaging with dynamic contrast-enhanced MRI (DCE-MRI) in human rectal cancer

Yuichi Kumagae¹, Yoshihiko Fukukurra¹, Koji Takumi¹, Hiroto Hakamada¹, Tomoyuki Okuaki², and Takashi Yoshiura¹

¹Department of Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan, ²Philips Electronics, Tokyo, Japan

Our purpose was to investigate potential correlations between the blood flow (BF) measured by pCASL and dynamic contrast-enhanced (DCE) MRI-derived pharmacokinetic parameters in rectal cancer. There were significant positive correlations between BF and K^trans (p = 0.006, r = 0.579) or K^ep (p = 0.002, r = 0.644). These results suggested that pCASL may have the potential to be a noninvasive alternative to DCE MRI.

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