Abstract #1538

Assessment of Tumor Hypoxia Using Tissue Oxygen Level Dependent in a Rabbit VX2 Liver Tumor model

Xinming Li¹, Shuping Qin¹, Wen Liang¹, Yingjie Mei², Yangguang Yuan¹, and Xianyue Quan¹

¹Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, China, ²Philips Healthcare, Guangzhou, China

There is attractive focus in developing non-invasive methods that assess tumor hypoxia. We applied tissue oxygen level dependent (TOLD) MRI to explore tumor oxygenation using VX2 liver tumor xenografts in a rabbit model. In this study，we demonstrated alteration in tumor oxygen inhalation and correlation in different hypoxia levels.

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