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Abstract #1553

An integrated, semi-automated 3D printed Breast DCE-MRI phantom solution to generate diverse pharmacokinetic curves

Nithin N Vajuvalli1, Amaresha Shridhar Konar1, Shivaprasad Ashok Chikop1,2, Ramesh Venkatesan2, and Sairam Geethanath1,3

1Medical Imaging Research Centre, Dayananda Sagar Institution, Bangalore, India, 2Wipro GE healthcare, Bangalore, India, 3Department of Radiology, Columbia University Medical Centre, New York, NY, United States

In vitro phantoms play a critical role in the assessment of novel Dynamic Contrast Enhanced MRI (DCE-MRI) methods related to acquisition and reconstruction, among other advantages such as repeatability and reproducibility. In this work, we demonstrate a 3D printed breast DCE-MRI phantom that is capable of producing diverse kinetic curves as those seen in human patients. The wash-in and wash-out characteristics were controlled through user controlled Ktrans values and the geometry of the phantom respectively. The phantom demonstrated in this work is 3D printed, cost effective, user interface controlled, and integrated with a peristaltic pump to obtain different kinetic curves.

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