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Abstract #1598

A non-Gaussian bi-exponential diffusion model with CUSP74 sampling for improved myocardial helix angle quantification and segmentation.

Cyril Tous1, Alistair Young1, and Beau Pontre1

1Anatomy and Medical Imaging, The University of Auckland, Auckland, New Zealand

The non-Gaussianity of diffusion at high b-value, leads to poor estimates of fast diffusion components when using diffusion models that assume Gaussian diffusion distributions. Including the diffusion kurtosis in a bi-exponential model allows better quantification of the partial volume effects when large b-values are used. This study investigates how this improved model can provide a better estimate of the helix angle in fixed heart specimens.

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