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Abstract #1599

Where's my water? Untangling the diffusion signal using the phasor representation

Michael J van Rijssel1, Martijn Froeling1, and Josien P W Pluim1,2

1Center for Image Sciences, UMC Utrecht, Utrecht, Netherlands, 2Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands

The recently proposed phasor representation and associated unmixing method allow separation of multi-exponentially decaying signals. This method has achieved promising results on diffusion MRI data and boasts sub-second analysis of full datasets on regular desktop PCs. This work investigates the noise propagation properties of this method and the influence of misplacing the vertex of a component in phasor space when performing unmixing. Results indicate that the phasor method is feasible and that the influence of component misplacement is systematic, but smaller than the errors due to noise at regular diffusion MR signal-to-noise-ratio levels.

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