Abstract #1628

DTI-based free-water elimination with T2-weighting using dedicated anisotropic diffusion fibre phantoms

Ezequiel Farrher¹, Kuan-Hung Cho², Richard Buschbeck¹, Husan-Han Chiang², Ming-Jye Chen², Farida Grinberg^1,3, N. Jon Shah^1,3,4,5,6, Chang-Hoon Choi¹, and Li-Wei Kuo^2,7

¹Institute of Neuroscience and Medicine 4, Forschungszentrum Jülich, Jülich, Germany, ²Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli, Taiwan, ³Department of Neurology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany, ⁴JARA – BRAIN – Translational Medicine, RWTH Aachen University, Aachen, Germany, ⁵Institute of Neuroscience and Medicine 11, Forschungszentrum Jülich, Jülich, Germany, ⁶Biomedical Imaging, School of Psychological Sciences, Monash University, Melbourne, Australia, ⁷Institute of Medical Device and Imaging, National Taiwan University College of Medicine, Taipei, Taiwan

In this work we demonstrate the use of two dedicated anisotropic diffusion fibre phantoms for the study of free-water elimination DTI. In particular, we make use of the recently proposed approach in which an extra dimension to the diffusion weighting, namely transverse relaxation weighting, is added to the model.

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