Abstract #1640

Spatially Varying Signal-Drift Correction in Diffusion MRI

Khoi Minh Huynh^1,2, Geng Chen^2,3, Wei-Tang Chang^2,3, Weili Lin^2,3, Dinggang Shen^1,2,3, and Pew-Thian Yap^2,3

¹Department of Biomedical Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, ²Biomedical Research Imaging Center (BRIC), The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, ³Department of Radiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States

The magnetic field in a MR scanner varies slightly in strength over time and causes the signal to drift. This drift can vary from voxel to voxel both in extent and direction. In this abstract, we show using diffusion MRI data that signal drift can be corrected more accurately when done locally than globally over the whole image volume¹. For this purpose, we employ a non-parametric correction method using non-diffusion-weighted scans interspersed in the diffusion-weighted image series.

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