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Abstract #1648

Error estimation and evaluation of spatial smoothing processing for diffusion kurtosis imaging

Suguru Yokosawa1, Yoshitaka Bito2, and Hisaaki Ochi1

1Research & Development Group, Hitachi, Ltd., Tokyo, Japan, 2Healthcare Business Unit, Hitachi, Ltd., Tokyo, Japan

DKI often suffers from error estimation such as unphysical negative kurtosis values which result in black voxels on mean kurtosis (MK) map. In this study, causes of the estimation error are investigated by using simulation. In addition, effect of smoothing processing is quantitatively evaluated in terms of reduction in estimation error and image sharpness. Our findings will be useful for clinical diagnosis using DKI.

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