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Abstract #1649

Improved diffusion propagator reconstruction using Hermite functions and compressed sensing

Gabriel Varela-Mattatall1,2, Carlos Castillo-Passi1,2, Joaquin Mura1, and Pablo Irarrazaval1,2,3

1Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile, 2Department of Electrical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 3Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile

Mean apparent propagator (MAP) reconstructs the diffusion pdf using a dictionary based on Hermite functions. The first element corresponds to a tensor approximation; and the following elements add non-gaussian components. To improve non-gaussian accuracy, one needs to increase the size of the dictionary, but it also increases the number of q-space samples for a robust optimisation. We propose the use of compressed sensing to efficiently increase the number of atoms in the dictionary by exploiting its sparsity for a better reconstruction.

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