Abstract #1674

Relationship between peripheral Interleukin 10 and white matter integrity in stable medicated schizophrenia

Gui Fu¹, Dongsheng Wu¹, Wenjing Zhang¹, Jieke Liu¹, Yuan Xiao¹, Li Yao¹, Jiaxin Zeng¹, John A Sweeney^1,2, and Su Lui¹

¹West China Hospital, Sichuan University, Chengdu, China, ²Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, Cincinnati, OH, United States

To our knowledge, this is the first time to study the association between plasm IL10 level and WM disruption in stable medicated schizophrenia using diffusion tensor imaging (DTI). The present study provided empirical evidence that dysregulation of inflammation contributes to anatomical dysconnectivity in schizophrenia.

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