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Abstract #1674

Relationship between peripheral Interleukin 10 and white matter integrity in stable medicated schizophrenia

Gui Fu1, Dongsheng Wu1, Wenjing Zhang1, Jieke Liu1, Yuan Xiao1, Li Yao1, Jiaxin Zeng1, John A Sweeney1,2, and Su Lui1

1West China Hospital, Sichuan University, Chengdu, China, 2Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, Cincinnati, OH, United States

To our knowledge, this is the first time to study the association between plasm IL10 level and WM disruption in stable medicated schizophrenia using diffusion tensor imaging (DTI). The present study provided empirical evidence that dysregulation of inflammation contributes to anatomical dysconnectivity in schizophrenia.

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