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Abstract #1675

Prediction of histological grade of hepatocellular carcinoma using quantitative diffusion-weighted magnetic resonance imaging: a retrospective multi-vendor study

Yoshio Kitazume1, Yusuke Ogihara1,2, and Ukihide Tateishi1

1Tokyo Medical and Dental University, Tokyo, Japan, 2JA Toride Medical Center, Ibaraki, Japan

Eighty-three patients with 100 histologically diagnosed hepatocellular carcinomas (HCCs) who preoperatively underwent diffusion-weighted (DW) imaging at any of 6 institutes were retrospectively studied. Receiver-operating characteristic analysis revealed that quantitative measurements such as the relative contrast ratio (RCR) and the contrast-to-noise ratio (CNR) between lesion and liver parenchyma on DW images were superior to the apparent diffusion coefficient (ADC) in predicting poorly differentiated HCCs, and intraclass correlation coefficients for the RCR tended to be greater than for the CNR and the ADC.

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