Abstract #1792

Relationships between brain structure and behavior in children with specific learning disabilities revealed by diffusion spectrum imaging

Yi-Chun Liu¹, Hsiao-Lan Sharon Wang², Shan-Chih Lee¹, and Jun-Cheng Weng^3,4

¹Department of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan, ²Department of Special Education, National Taiwan Normal University, Taipei, Taiwan, ³Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan, ⁴Department of Psychiatry, Chang Gung Memorial Hospital, Chiayi, Taiwan

We used diffusion spectrum imaging (DSI) to investigate the relationships between brain structure and behavior in children with specific learning disabilities (SLD). The correlation between reading comprehension scores and the DSI indices was found in corpus callosum. The correlation between Chinese character recognition and the DSI indices was found in cingulate and corpus callosum. The correlation between tone awareness scores and the DSI indices was found in cingulate, superior frontal gyrus and corpus callosum. In summary, SLD not only had difficulty reading and spelling individual words but also more likely to have poorer phonological awareness.

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