Abstract #1799

Quantification of Diffusion Tensor Imaging (DTI) in the Pediatric Spinal Cord: Application to Clinical Evaluation

Aashim Bhatia¹, Bryson Reynolds², Samantha By², Bhavesh Ramkorun², Quinn Weinberg², Mark Adams³, John Clifton Wellons III⁴, and Seth Smith²

¹Radiology, Vanderbilt Childrens’s Hospital, Nashville, TN, United States, ²Vanderbilt University Institute of Imaging Science, Nashville, TN, United States, ³Urology, Vanderbilt Childrens’s Hospital, Nashville, TN, United States, ⁴Neurosurgery, Vanderbilt Childrens’s Hospital, Nashville, TN, United States

The goal of the study was to apply optimized Diffusion Tensor Imaging (DTI) in the pediatric spinal cord and quantified to determine normative DTI-derived indices based on age. DTI was acquired in 35 patients, 22 being normal and AD, FA, MD, and RD were calculated.

DTI of the spinal cord in the pediatric population can be performed in the clinical setting to produce reliable DTI values. AD and MD demonstrated statistically significant changes based on age in both normal patients and the complete patient population.

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