Abstract #1838

SUBCORTICAL VOLUMETRIC CHANGES IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER: ROLE OF MRI

Mariia Viktorovna Rezakova¹, Elena Andreevna Filimonova¹, Khurshed J. Ibrogimov², Olga Anatolevna Subbotina¹, and Alexandr Vladimirovich Shevchenko¹

¹Stare Scientific-Research Institute of Physiology and Basic Medicine, Novosibirsk, Russian Federation, ²Novosibirsk State University, Novosibirsk, Russian Federation

We analyzed subcortical structures in patients with MDD (N=15) and control (N=15) using FreeSurfer. Patients with MDD had significantly lower left thalamus (p<0,01), left putamen (p<0,05), left hippocampus (p<0,05) and some hippocampal subfields volumes, relative to control. We found correlations (p<0,05) between patient’s age and putamen volume (r= -0,56), number of depressive episodes and molecular layer volume (r= -0,52). We didn’t reveal correlation between segmentation data and MDD severity.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.