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Abstract #1880

Template maps of vascular function and structure in the healthy brain

Endre Grøvik1, Kyrre Eeg Emblem1, Ingrid Digernes1, Line Brennhaug Nilsen1, Cornelius Eichner2, Kourosh Jafari 2, Thomas Witzel2, Behroze Vachha2, Elizabeth Gerstner2, Jayashree Kalpathy-Cramer2, Kawin Setsompop 2, and Steven Stufflebeam 2

1Department for Diagnostic Physics, Oslo University Hospital, Oslo, Norway, 2Athinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, Boston, MA, United States

In recent years, Vessel Architectural Imaging (VAI) has emerged as a promising tool in tumor diagnosis to reveal unique MRI-based information on vessel architecture, hemodynamic efficacy and metabolic activity. Healthy control data may further advance our knowledge on the VAI method and its underlying mechanisms, as well as serve as study controls. Here we propose a set of healthy-tissue template maps of all VAI derived parameters which may act as a toolbox to identify anomalies of various vascular brain diseases and ultimately help improve diagnostic and outcome assessment in clinical settings.

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