Abstract #1897

3D multi-shot(ms) Spin-Stimulated Echo(STE) EPI sequence Technique for accurate T1 quantification of contrast uptake within vulnerable large artery plaque

Seong-Eun Kim¹, J Scott Scott McNalley¹, Adam de Havenon ², Dennis L Parker¹, and Gerald S Treiman ³

¹UCAIR, Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, ²Department of Neurology, University of Utah, Salt Lake City, UT, United States, ³Department of Veterans Affairs, VASLCHCS, Salt Lake City, UT, United States

Large artery atherosclerotic disease is one of the most common causes of ischemic stroke. Post-contrast plaque enhancement (PPE), which may result from endothelial dysfunction or be secondary to intraplaque inflammation, is a vulnerable plaque feature that correlates with increased stroke risk independent of stenosis. Although PPE can be detected with vessel wall MRI better quantitative methods to measure PPE are needed. This work presents a new 3D high resolution T₁mapping technique for accurate T₁ quantification of contrast uptake within vulnerable large artery plaque.

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