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Abstract #1899

The diagnostic performance of DCE-MRI in glioma grading: A systematic review and meta-analysis

Zhe Liu1, Xiang Li1, Ting Liang1, Tong Yi Bian1, Miao Miao Wang1, Li Qin Sun1, Gang Niu1, and Jian Yang1

1the first affiliated hospital of XI'AN jiaotong university, XI'AN, China

Different parameters of Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been provided for noninvasive evluating gliomas pathology status. But the diagnostic performance of those parameters were variant among the recent reports during different type of gliomas. This study included 17 DCE-MRI studies regarding to differentiating different types of gliomas. The meta-analysis results demonstrated that Ve parameter of DCE-MRI has higher AUC in distinguishing HGGs from LGGs, gradeⅡ from grade Ⅲ and grade Ⅲ from gradeⅣ,respectively, Ktrans has higher AUC in distinguishing gradeⅡfrom grade Ⅳ; Among all the pamameters from DCE, Ktrans,Ve,Vp showed higher diagnostic performance in distinguishing different grade of gliomas.

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