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Abstract #1900

Remote effects of hemodynamic impairment on network efficiency in chronic steno-occlusive disease of the anterior circulation: A resting-state functional MRI study

Junjie Wu1, Seena Dehkharghani2, Fadi Nahab3, Jason W. Allen1, Ranliang Hu1, and Deqiang Qiu1

1Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States, 2Department of Radiology, New York University, New York, NY, United States, 3Department of Neurology, Emory University School of Medicine, Atlanta, GA, United States

In this abstract we explored remote effects of cerebrovascular hemodynamic impairment on the efficiency of functional connectivity in patients with chronic, anterior circulation steno-occlusive disease. We further evaluated the correlation between network efficiency and cerebrovascular reactivity (CVR), a measure of cerebral hemodynamics.

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