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Abstract #1947

ROLE OF SUSCEPTIBILITY-WEIGHTED ANGIOGRAPHY (SWAN) QUANTITATIVE MAPPING IN PARKINSON DISEASE DIAGNOSIS

Mariia Viktorovna Rezakova1, Khurshed J. Ibrogimov2, Elena Andreevna Filimonova1, Olga Anatolevna Subbotina1, and Alexandr Vladimirovich Shevchenko1

1Stare Scientific-Research Institute of Physiology and Basic Medicine, Novosibirsk, Russian Federation, 2Novosibirsk State University, Novosibirsk, Russian Federation

We designed SWAN-based algorithm for assessment the pattern of ferromagnetic substances spatial distribution in brain tissue in patients with Parkinson disease. We achieved high diagnostic accuracy in identification of microhemorrhagic changes. In 27 of the 43 patients with PD were observed hemorrhagic lesions in the chronic phase. In the control group, such changes were not observed. In addition, patients with PD had specific localization of lesions (in the epiphysis and vascular plexus).

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