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Abstract #1955

Comparison between two different post-processing techniques in the presurgical evaluation of Focal Cortical Displasya in a paediatric population.

Elena Bassanelli1, Maria Camilla Rossi Espagnet2, Nicola Pietrafusa3, Luca De Palma3, Nicola Specchio3, Daniela Longo2, and Antonio Napolitano1

1Medical Physics Department, IRCCS Bambino Gesù Children’s Hospital, Rome, Italy, 2Imaging Department, IRCCS Bambino Gesù Children’s Hospital, Rome, Italy, 3Department of Neurosciences, IRCCS Bambino Gesù Children’s Hospital, Rome, Italy

The purpose of this study is to compare two different techniques for cortical dysplasia detection: Opti-MAP and the SUPR-FLAIR. The Opti-MAP is a children-optimized version of the Morphological analysis program (MAP), which is able to detect the “blurred-junction”, peculiar characteristics of focal cortical dysplasia in children, thanks to a voxel-based morphological analysis in which neuroanatomical differences are detected by comparison with a normal template. The SUPR-FLAIR analysis, instead, is a technique able to highlight hyperintensities in FLAIR images. These methods have been applied on paediatric subjects affected by pharmaco-resistant epilepsy.

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