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Abstract #1956

Imaging and involvement of visual pathways in children undergoing epilepsy surgery

Luis Miguel Lacerda1, Martin Tisdall2, Gavin Winston3, Sian Handley4, Alki Liasis4, and Chris A Clark1

1Developmental Imaging and Biophysics Section, UCL Great Ormond Street Institute of Child Health, London, United Kingdom, 2Neurosurgery, UCL Great Ormond Street Institute of Child Health, London, United Kingdom, 3Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, United Kingdom, 4Ophthalmology, UCL Great Ormond Street Institute of Child Health, London, United Kingdom

Surgery is a key approach for achieving seizure control in children with epilepsy but it can affect or be in the vicinity of the optic radiations. Whilst tractography has shown that damage to optic radiations leads to postoperative visual field defects in adults it has not yet been properly explored in children. In this study we successfully performed tractography reconstructions in a paediatric cohort undergoing surgery. Furthermore, we showed that in cases with pre- and post-surgical visual function assessment, involvement of optic radiations corresponded to visual function disturbances. This highlights the importance of tractography to aid pre-surgical evaluation in children.

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