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Abstract #2018

Follow up research of hippocampal subfield in patients with mild Alzheimer's disease

Ying Liu1 and Lizhi Xie2

1Radiology Department, Peking University Third Hospital, Beijing, China, 2GE Healthcare, China, Beijing, China

The aim of this study is to evaluate the atrophy pattern of hippocampal subfield and follow up the changes of hippocampal subfield by using automatic segmentation tool in patients with mild AD. The results indicate that volumes of hippocampal subfield decrease in patients with mild AD, and the declination are positive correlated with clinical scores. We conclude that substructures of hippocampal might serve as a good index to characterize subtle changes in AD patients.

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