Abstract #2027

Iron Deposition in Alzheimer's Dementia Hippocampus is Associated with Increased R2* Values

Grayson Tarbox¹, Amin Nazaran¹, Neal Bangerter¹, and Jonathan J. Wisco²

¹Electrical Engineering, Brigham Young University, Provo, UT, United States, ²Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States

We describe the utilization of UTE-3D Cones to create T2* maps of iron deposition in the hippocampus of an Alzheimer’s dementia subject, but not in a corticobasal degeneration subject. These results are consistent with histopathological studies involving post-mortem human brain tissue. UTE-3D Cones could be a promising imaging protocol for AD diagnostic imaging.

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