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Abstract #2027

Iron Deposition in Alzheimer's Dementia Hippocampus is Associated with Increased R2* Values

Grayson Tarbox1, Amin Nazaran1, Neal Bangerter1, and Jonathan J. Wisco2

1Electrical Engineering, Brigham Young University, Provo, UT, United States, 2Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States

We describe the utilization of UTE-3D Cones to create T2* maps of iron deposition in the hippocampus of an Alzheimer’s dementia subject, but not in a corticobasal degeneration subject. These results are consistent with histopathological studies involving post-mortem human brain tissue. UTE-3D Cones could be a promising imaging protocol for AD diagnostic imaging.

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