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Abstract #2037

T1-weighted imaging of the orbitofrontal cortex in individuals with dental braces using 2D FLAIR

Sander Lamballais1,2, Piotr Wielopolski3, Aad van der Lugt3, Vincent Jaddoe1,2,4, Mohammad Arfan Ikram1,3,5, Tonya White3,6, and Juan Antonio Hernández Tamames3

1Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands, 2The Generation R Study Group, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands, 3Department of Radiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands, 4Department of Pediatrics, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands, 5Department of Neurology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands, 6Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands

Neuroimaging studies in (pre)adolescent populations have steadily increased in number over the last decade. However, dental braces are common amongst (pre)adolescents and introduce metal-related artifacts in the images. Excluding individuals with braces from epidemiological studies may lead to selection bias and missingness in repeated measures. To this end we configured a T1-weighted 2D FLAIR sequence and compared it to a T1-weighted 3D SPGR sequence. Compared to SPGR, the FLAIR sequence suffered less from metal artifacts and performed similarly in cortical reconstruction and volumetric segmentation. Thus, T1-weighted 2D FLAIR may be a useful alternative for neuroimaging in participants with dental braces.

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