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Abstract #2042

Quantitative assessment of automatic cortical surface reconstructions from Wave-CAIPI MPRAGE: A validation study

Yulin V Chang1, Stephen F Cauley2,3, Wei Liu4, Daniel Polak2,5, Borjan Gagoski6, Berkin Bilgic2,3, Kawin Setsompop2,3, and Jonathan R Polimeni2,3

1Siemens Medical Solutions USA, Boston, MA, United States, 2A. A. Martinos Center for Biomedical Imaging, Radiology, MGH, Charlestown, MA, United States, 3Harvard Medical School, Boston, MA, United States, 4Siemens Magnetic Resonance, Shenzhen, China, 5Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany, 6Boston Children's Hospital, Boston, MA, United States

Structural imaging of the brain using conventional MPRAGE at high resolution is vulnerable to motion artifacts due to prolonged scan times. MPRAGE acquired with wave-CAIPIRINHA technique (waveMPRAGE) and a multi-channel receive coil can significantly improve imaging speed with minimal noise penalty. We show that head motion can be observed from multiple waveMPRAGE scans in a time span similar to a single conventional MPRAGE, and that registering and averaging multiple short (approx. 1 min) waveMPRAGE repetitions produces reliable and reproducible cortical surfaces reconstructed automatically using FreeSurfer.

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