Alzheimer’s disease (AD) is one of the most common forms of dementia, marked by progressively degrading cognitive function. The cerebellum plays a role in AD development, but its predictive contribution to early stages of AD remains unclear. We used MRI machine learning based classification within myelin and grey matter of the whole, anterior and posterior cerebellum and the whole brain, between individuals within the first two early stages of dementia and typically ageing controls. Our findings suggest myelin and grey matter loss in early stages of AD, with distinct patterns of anterior and posterior cerebellar atrophy for each tissue property.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords